建立于一百年前的埃克赛特疗养院曾经收治许多心理有障碍的青少年，此后入院治疗的病患逐渐攀升，医疗条件则每况愈下，甚至不断爆出青少年被虐待致死的丑闻。如今该疗养院早已废弃，此地闹鬼的传闻却越传越凶，当然这无法吓退那些寻求刺激、胆大妄为的年轻人。某天，帕特里克（Kelly Blatz 饰）和好友罗里（Michael Ormsby 饰）、诺尔斯前往该疗养院参加这里举行的狂欢派对。年轻人们寻欢作乐，各取所需。一夜狂欢过后，从酒精麻醉中渐渐醒来的年轻人们闲聊打屁。稍后众人挑战禁忌，举行招魂仪式，结果见到了超自然的一幕。
未过多久，罗里仿佛被恶魔附体一般狂暴凶悍，而更为恐怖的经历还等在后面……
因流感感染的死者突然复活，变成丧尸开始疯狂撕咬活人，被咬后的活人纷纷变成丧尸，一场末日丧尸之战自此开始...
A sheltered, intelligent college student DOUG (RJ Mitte of "Breaking Bad") changes his life forever when he hires an underachieving driver SCOTT (Ray William Johnson of "Equals Three"). In order to escape his oppressively loving MOTHER (Daphne Zuniga), Doug agrees to go on a spontaneous road trip with Scott and his college crush STEPHANIE (Paloma Kwiatkowski of "Bates Motel"). ...
